Really? how would it be more of a strain on the fuel pumps? I've never had that problem with any of the cars Ive had!
As Shadow99611 suggested, this becomes problematic because your pump will begin pulling air at lower fuel levels, which results in it overheating. With a fuel tank that is 1/4th full, you might expect your car to be fine, but you must also consider that you will not always be driving on perfectly level terrain, and therefore the fuel in the tank will also not be just sitting flat. When you live in an area with lots of hills, such as I do, inclining the car a given way will alter the distribution of fuel in the tank (it is the same as tilting a glass full of water, the water tilts with the glass). Depending on the direction of the tilt (either to or away from the fuel pump inlet) the pump may begin to partially pull air, even with 1/4th remaining fuel.
A good example of this occurs when I am driving up or down hills. Again, depending on the direction of the tilt of my car while driving on such terrain, the fuel indicator can drop down to the "E" level with 1/4th remaining fuel, or appear to be 1/2 full until the car returns to driving on a flat surface.
Hope this clears things up, Kai.